St Cecilia's College is a secondary school located in Derry, Northern Ireland. It is a Catholic-maintained girls school with an enrolment of 947 pupils aged 11–18 and is located in the Northland Road area of Derry. It has 60 teaching staff. The college has decanted to the Northland Road to facilitate the construction of a new building which opened for the start of term in September 2010. It is within the Western Education and Library Board area.
In March 2001 a programme for the extension and refurbishment of the College was announced under Public-private partnership arrangements. In March 2006 it was announced that the College would be granted specialist status from September 2006. As a specialist school it will receive £100 per pupil for the four years of designation and a £100,000 capital grant to support development of the specialism.